What is Frameshift Mutation? Definition of Frameshift Mutation A frameshift mutation is a genetic alteration caused by the insertion or deletion of nucleotides in a DNA sequence, which shifts the reading frame of codons and results in the production of an altered and typically nonfunctional protein. Causes of Frameshift Mutation The main causes of frameshift … Read more
What is Chromosomal mutation? Definition of Chromosomal Mutation Chromosomal mutation refers to alterations in the structure or number of chromosomes within a cell, which can impact genetic information and potentially lead to various genetic disorders. Causes of Chromosomal Mutation Mechanism of Chromosomal Mutation Chromosomal mutations arise through various mechanisms that can be broadly categorized into … Read more
What is Somatic Mutation? Definition of Somatic Mutation A somatic mutation is a genetic change that occurs in non-reproductive cells after fertilization, which typically does not get passed on to offspring. Causes of Somatic Mutation Several factors and stressors can contribute to somatic mutations. These can be categorized into endogenous factors, chemical mutagens, physical mutagens, … Read more
What is Induced Mutation? Mechanism of induced mutation Induced mutations occur when external agents, known as mutagens, alter the structure or sequence of DNA. These mutations can arise through several mechanisms that affect how DNA bases interact or replicate. Let’s explore the primary mechanisms responsible for induced mutations. Base Replacement by Base Analogs Base analogs … Read more
Mutations are changes in the genetic material of an organism. These alterations can occur in various ways, and they play a fundamental role in biological diversity and evolution. Broadly, mutations can be classified into two major categories: gene mutations and chromosomal mutations. Gene mutations, also known as point mutations, occur when a change takes place … Read more
What is Mutation? Definition of Mutation Mutation is a permanent change in the DNA sequence of a gene or chromosome, which can result from errors in replication or environmental factors and can affect an organism’s traits. Terminology of Mutation Characteristics of Mutation Classification and types of Mutation Causes and Mechanisms of Mutation Understanding the causes … Read more
What is Crossing over? Definition of Crossing over Crossing over is the exchange of genetic material between non-sister chromatids of homologous chromosomes during prophase I of meiosis, resulting in new combinations of genes. Characteristics of Crossing over At which stage Crossing over occurs? Types of Crossing over Crossing over can be categorized based on its … Read more
What is Two-Point Cross? A two-point cross is a genetic mapping technique used to determine the recombination frequency between two specific genes located on the same chromosome. In this method, a test cross is performed between a heterozygous individual (carrying two different alleles for the genes of interest) and a homozygous recessive individual (which has … Read more
What is Linkage? Definition of Genetic Linkage Genetic linkage is the tendency for genes located on the same chromosome to be inherited together due to their physical proximity. Exploring Terms Related to Genetic Linkage Characteristic of Linked Genes Linked genes are genes that are located close together on the same chromosome and tend to be … Read more
What is Pedigree? What is Pedigree Analysis? Pedigree Analysis Definition Pedigree analysis is a genetic tool used to trace the inheritance patterns of traits or disorders through generations of a family, helping to predict the likelihood of their occurrence in offspring based on familial history. Basic Steps of Pedigree Analysis Pedigree analysis involves several systematic … Read more
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