Tumor – Types, Tumor Antigens, Risk Factors

Tumors - Types, Tumor Antigens, Risk Factors

Tumor is also called neoplasm. It is an abnormal solid mass of tissue. It is formed when cells multiply in uncontrolled way or when cells do not die at proper time. Tumor is different from cyst. Cyst is usually filled with fluid or air. But tumor is a solid growth. It has no useful function … Read more

Immunotherapy For Tumor – Principle, Types, Mechanism

Immunotherapy For Tumors

Immunotherapy for tumors is a treatment method where the body immune system is used to act against cancer cells. It helps immune cells to identify and kill tumor cells. It is not like chemotherapy, because chemotherapy directly attacks dividing cells. In immunotherapy, immune response is increased or trained against cancer antigen. The main target is … Read more

Chronic granulomatous disease (CGD)  – Causes, Pathogenesis, Symptoms, Diagnosis, Treatment

Chronic granulomatous disease (CGD) 

Chronic granulomatous disease (CGD) is a rare inherited primary immunodeficiency disease. It affects the phagocytic cells mainly neutrophils and macrophages. These cells are normally used to kill the invading bacteria and fungi. It is caused due to mutation in genes which are related with NADPH oxidase enzyme complex. Due to defect in this enzyme complex, … Read more

Immunodeficiencies – Definition, Types, Mechanism, Examples, Animal models

Immunodeficiencies - Definition, Types, Animal models(Nude and SCID mice)

Immunodeficiency is a condition in which the immune system becomes weak or defective. It may occur due to defect in lymphocytes, phagocytes or complement system. In this condition, the body becomes more susceptible to infections. Immunodeficiency disorders are conditions in which the immune system becomes fully or partly impaired. It occurs due to defect, failure … Read more

Hypersensitivity – Definition, Types, Mechanisms, Examples

Hypersensitivity - Definition, Types, Mechanisms, Examples

Hypersensitivity is an abnormal immune reaction of the body. It is an exaggerated response against an antigen. This reaction causes tissue damage and different physiological disturbances in the body. Normally immune system protects the body from harmful substances. But in hypersensitivity, the same immune system reacts in harmful way. It may react against harmless substances … Read more

Cytotoxic T cells – Development, Activation, Functions

Cytotoxic T cells

Cytotoxic T cells are special type of white blood cells present in the adaptive immune system. These cells are commonly called CD8⁺ T cells. They are mainly used to destroy the body cells which are infected by virus, intracellular pathogens or changed into cancerous cells. Cytotoxic T cells continuously move in the body and check … Read more

Cell Mediated Immune Response – Definition, Mechanism, Cells Involved

Cell Mediated Immune Response 

Cell mediated immune response is a type of adaptive immune response in which T lymphocytes directly react against the foreign antigen. It does not mainly depend on circulating antibody. It is mostly active against intracellular pathogens, infected cells and some abnormal cells. This immune response is mainly carried out by cytotoxic T cells (CD8⁺) and … Read more

Immunological Tolerance – Definition, Mechanism, Types

Immunological Tolerance - Definition, Mechanism, Types

Immunological tolerance is a state of specific unresponsiveness of the immune system against a particular antigen. In this condition, the immune system does not produce destructive reaction against that antigen. It is a normal protective mechanism of the body. It helps the immune system to distinguish between self and non-self substances. The immune system can … Read more

Spirogyra – Definition, Structure, Life Cycle, Diagram, Reproduction

Morphology or Structure of Spirogyra

Spirogyra is a filamentous green algae. It is free floating in nature. It is mainly found in freshwater bodies like ponds, lakes and slow moving streams. It is commonly called water silk or pond scum. This name is given because its filament is soft, slimy and slippery. The filament is covered by mucilaginous sheath. The … Read more