Theta Model of Replication – Steps, Applications, Examples

Theta Model of Replication - Definition, Mechanism

What is Theta model of DNA Replication? The theta model of DNA replication is a mechanism for DNA replication which occurs in circular DNA molecules, in particular, those of bacteria, and also the mitochondria and chloroplasts. True to its name, this replication process creates an intermediate structure during replication that resembles the Greek letter theta … Read more

Telomerase – Structure, Mechanism, Regulation, Functions

Telomeres and Telomerase

What is Telomerase? Telomerase (terminal transferase) is a ribonucleoprotein enzyme that extends telomeres, the repetitive nucleotide sequences at the ends of eukaryotic chromosomes. Telomeres function as protective caps, stopping chromosome ends from being erroneously perceived as DNA damage or from bonding with neighboring chromosomes. Most eukaryotes use telomerase to maintain their telomeres, but some organisms, … Read more

Telomeres – Structure, Aging, Shortening, Functions

Telomeres and Telomerase

What Are Telomeres (telomere)? At the ends of linear eukaryotic chromosomes are specialized structures called telomeres. DNA degradation is prevented by repetitive nucleotide sequences of the telomere, which caps and so stabilizes chromosomal DNA during cell division. The termini of chromosomes not only have no translation product but instead have a highly important role in … Read more

Various model of Replication – Theta, rolling circle, and linear DNA replication

Various model of Replication - Theta, rolling circle, and linear DNA replication

Plasmids are small circular molecules of DNA that exist independently of chromosomal DNA within a cell. Because they replicate independently, these molecules are called replicons. The plasmids have an origin of replication known as the ori site from which replication begins. Plasmids encode a few of their own proteins, but when it comes to replication … Read more

What is DNA Replication? – Steps, Enzymes, Mechanism, Applications

DNA Replication Mechanism, Definition, Requirements, Steps

What is DNA Replication? Definition of DNA Replication DNA replication is the biological process by which a cell duplicates its DNA molecule, producing two identical copies from one original DNA strand, ensuring the transmission of genetic information during cell division. DNA Replication Enzymes and Proteins DNA replication is a fundamental biological process, relying on various … Read more

Eukaryotic Gene Regulation – Mechanisms, Regulatory Elements

Regulation of Transcription in Eukaryotic Cells

Eukaryotic gene regulation is a fundamental aspect of molecular biology that plays a critical role in the expression of genes within eukaryotic cells. This intricate system governs when, where, and how much specific genes are expressed, which is essential for the proper development and functioning of organisms, ranging from unicellular protozoa to complex multicellular organisms, … Read more

Enhancers and silencers – Definition, Location, Examples, Functions

Enhancers and silencers - Definition, Location, Examples, Functions

What are Enhancers and silencers? What is Enhancer? Enhancers play a critical role in regulating gene expression in both prokaryotes and eukaryotes. They are specific regions of DNA that, despite their distance from the genes they influence, serve as crucial elements for the transcriptional activation of genes. Below is a detailed breakdown of what enhancers … Read more

DNA Ligase – Structure, Types, Mechanism, Functions

DNA Ligase - Structure, Types, Mechanism, Functions

What is Ligase? In biochemistry, ligases are a class of enzymes that incorporate joining of two large molecules by forming new bond. This process which is referred to as ligation, commonly entails a hydrolysis of a indivisible chemical group of one of the substrates which allows formation of new linkages that include C-O, C-S or … Read more

DNA Helicases – Structure, Types, Mechanism, Functions, Examples

DNA Helicases - Structure, Types, Mechanism, Functions, Examples

What is Helicase? What is DNA Helicase? History of DNA Helicases The history of DNA helicases begins with their discovery in the mid-1970s. These enzymes, crucial for unwinding DNA strands, have been extensively studied across a wide range of organisms. From bacteria to plants and humans, research on helicases has revealed their essential role in … Read more

Recombinant DNA Technology – Steps, Application, Tools, and Limitations

Recombinant DNA Technology Steps, Application, Tools, and Limitations

What is Recombinant DNA Technology? Definitions of Recombinant DNA Technology Recombinant DNA technology is a method used to manipulate and combine DNA from different sources to create new genetic combinations. It involves inserting genes from one organism into the DNA of another, allowing for the production of specific proteins or traits not naturally found in … Read more

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