Biological Consequences of Complement Activation

Biological Consequences of Complement Activation

Complement system is an important part of innate immune system. It acts as first line defense against invading pathogens, foreign materials and damaged cells. It helps the body to remove microbes and abnormal cells. It is made up of more than 40 proteins. Most of these proteins circulate in blood in inactive form. When danger … Read more

Classical Pathway – Definition, Components, Steps, Regulation, Functions

Classical Pathway of Complement Activation

Complement system is an important part of immune system that helps in the defense of body against invading microorganisms. It is present in the blood and tissue fluid in inactive form. It contains more than 30 plasma proteins which are activated during infection or immune reaction. These proteins are mostly present as inactive proenzymes. When … Read more