Passive Immunity – Definition, Types, Characteristics, Examples

Passive Immunity - Definition, Types, Characteristics, Examples

Passive immunity is the type of immunity in which ready-made antibodies are given to a person or animal from outside source. It is not produced by the own immune system of the body. In this immunity the immune system remain passive and only gets protection. It gives very quick protection against infection, toxin or any … Read more

Complement System – Definition, Activation, Effects, Regulation

Complement System Definition, Activation, Effects, Regulation

Complement system is a group of blood proteins that takes part in innate immune response. It helps in killing microbes, inflammation and phagocytosis. It also increases the action of antibodies and immune cells. Complement system is an important part of innate immune system. It acts as the first line defense against invading pathogens like bacteria, … Read more

Biological Consequences of Complement Activation

Biological Consequences of Complement Activation

Complement system is an important part of innate immune system. It acts as first line defense against invading pathogens, foreign materials and damaged cells. It helps the body to remove microbes and abnormal cells. It is made up of more than 40 proteins. Most of these proteins circulate in blood in inactive form. When danger … Read more

Classical Pathway – Definition, Components, Steps, Regulation, Functions

Classical Pathway of Complement Activation

Complement system is an important part of immune system that helps in the defense of body against invading microorganisms. It is present in the blood and tissue fluid in inactive form. It contains more than 30 plasma proteins which are activated during infection or immune reaction. These proteins are mostly present as inactive proenzymes. When … Read more

Alternative Pathway – Definition, Components, Steps, Regulation, Functions

Alternative Pathway of Complement System

Complement system is an ancient part of innate immune system. It acts as first line defence of body against infections. It is present in blood and tissue fluid. It is made up of about 50 plasma and membrane bound proteins. These proteins remain mostly inactive form. After getting proper signal, they become activated one after … Read more

Lectin Pathway – Definition, Components, Step, Functions, Regulation

Lectin Pathway of the Complement System

Complement system is an important part of the innate immune system which acts as first line defence against infections. It protects the body from foreign microorganisms and also helps in removing damaged cells and immune complexes. It is present in blood and tissue fluid in inactive form. It is made up of many soluble plasma … Read more

Expression of MHC Molecules

Expression of MHC Molecules

Major Histocompatibility Complex (MHC) molecules are surface proteins of cells. They present antigenic peptide to T cells. It is required for immune recognition of foreign antigen. Expression of MHC molecules is different in different cells. MHC class I molecules are present on almost all nucleated cells. They are absent or very little present on non-nucleated … Read more

MHC Genes – H-2 Complex and HLA Complex

MHC Genes - H-2 Complex and HLA Complex

Major Histocompatibility Complex (MHC) genes are a group of closely linked genes present in vertebrate DNA. These genes are highly diverse and they play important role in adaptive immune system. In human, this region is known as Human Leukocyte Antigen (HLA) complex. The HLA complex is present on chromosome 6. It contains more than 200 … Read more

Antigen-Antibody Interaction Reaction – Definition, Types, Examples, Properties

Antigen-Antibody Interaction Reaction - Definition, Types, Examples, Properties

Antigen-antibody interaction reaction is a specific binding reaction between an antigen and its corresponding antibody. In this reaction the antibody recognizes the specific part of antigen, which is called epitope. The binding site of antibody is present in the hypervariable region and it is complementary to the epitope. This reaction is very important in humoral … Read more

Antigen – Definition, Types, Structure, Detection, Properties

Antigen - Definition, Types, Structure, Detection, Properties

Antigen is a foreign molecule which is recognized by immune system. It may be protein, polysaccharide, lipid or nucleic acid. It is called antigen because it can generate antibody or bind with antibody. Antigen is mostly found on the surface of bacteria, virus, fungi and parasites. It may also present on normal human cells, cancer … Read more