The extrinsic pathway of apoptosis is a process whereby cells initiate programmed cell death in response to external signals, such as those from neighbouring cells or the immune system. This route is activated by the binding of particular ligands to cell surface death receptors, such as tumour necrosis factor (TNF) or Fas ligand. The binding … Read more

Intracellular stimuli, such as DNA damage, predominantly trigger apoptosis via the intrinsic route. The intrinsic apoptosis pathway, which is comprised of conserved signalling proteins, is physically connected with mitochondria and sensitive to mitochondrial oxidative stress in vertebrates. Members of the Bcl family linked to the mitochondrial membrane have an effect on the process, including the … Read more

What are Platelets (Thrombocytes)? Platelets (Thrombocytes) Definition Platelets, also known as thrombocytes, are anucleated cells derived from megakaryocytic cells in the bone marrow. They are the second most abundant cells in the blood circulation and play a crucial role in maintaining hemostasis by initiating blood clotting. Platelets also have non-hemostatic immune functions and can release … Read more

Storage Granules Definition Structure of Storage Granules Storage Granules in Bacteria Storage Granules Function Storage granules have several important functions in cells, including: Overall, storage granules play a critical role in maintaining cellular homeostasis and allowing cells to adapt to changing environmental conditions. FAQ References

Cilia Definition Characteristics of Cilium Structure of Cilium Cilia are extracellular protrusions that are membrane-bound, microtubule-containing, and formed from centrioles. They are structurally durable, as well as flexible and dynamic, having different mechanisms that regulate their composition and functions. On the basis of the patterns of microtubules found in the axonemes of the cilia, motile cilia … Read more

What is Fluid Mosaic Model of Plasma Membrane? – Fluid Mosaic Model Definition The fluid mosaic model is one method to comprehend biological membranes, consistent with the majority of experimental findings. According to this hypothesis, membrane components such as proteins and glycolipids form a mobile mosaic in the fluid-like environment formed by a sea of … Read more

What is Cell proliferation? What is Normal cell proliferation? The delicate balancing act between cell growth, division, differentiation, and death is what allows for normal cell proliferation, an essential function in the body. Diseases can be caused by disruptions in any of these systems, thus they’re all crucial. Proliferation and apoptosis are two processes that … Read more