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Have you ever wondered how your body creates new cells? Or how genetic information is passed down from one generation to the next? The answer lies in a fascinating process called DNA replication. In this article, we’ll dive deep into the world of eukaryotic DNA replication, exploring its intricacies, importance, and the cutting-edge research surrounding … Read more
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What is Prokaryotic DNA Replication? Structure of Ori C OriC (Origin of Chromosome) is the specific locus in Escherichia coli where DNA replication is initiated. This critical region is located at approximately the 84.5 mpu position on the E. coli genome, situated opposite to the replication termination site. The structure of OriC is characterized by … Read more
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What is a Retrovirus? Definition of Retrovirus A retrovirus is a type of RNA virus that replicates by converting its RNA genome into DNA through the enzyme reverse transcriptase. This DNA is then integrated into the host cell’s genome, where it directs the production of new viral particles. Retroviruses are associated with various diseases, including … Read more
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Streptococcus pneumoniae Overview Streptococcus pneumoniae, commonly known as pneumococcus, is a Gram-positive, spherical bacterium. It is alpha-hemolytic and belongs to the genus Streptococcus. Discovered by Louis Pasteur and George Sternberg in the late 19th century, it is a significant human pathogen, especially noted for causing pneumonia. S. pneumoniae typically appears as lancet-shaped diplococci, meaning it … Read more
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What is Python Programming? Programming in Python refers to the process of creating computer programmes using the Python programming language. Python is a high-level, interpreted programming language renowned for its readability and simplicity. It was developed by Guido van Rossum and published for the first time in 1991. Python is extensively employed in numerous fields, … Read more
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What is Sanger Sequencing? Principle of Sanger Sequencing The principle of Sanger sequencing is rooted in the termination of DNA strand elongation by dideoxynucleotide triphosphates (ddNTPs). These ddNTPs are modified versions of normal DNA nucleotides that lack a 3’ hydroxyl group, which is essential for forming a phosphodiester bond. Without this bond, the DNA strand … Read more
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What is Whole Genome Sequencing? Principle of Whole Genome Sequencing The principle of whole genome sequencing (WGS) revolves around the complete sequencing of an organism’s DNA, encompassing both coding and non-coding regions. This method provides a thorough understanding of the genome, detailing the genes, regulatory elements, and variations present. WGS begins with the extraction of … Read more
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What are Gram-negative bacteria? Cell wall of the Gram-negative is more complicated than the Gram-positive cell wall. The amount of peptidoglycan present in the Gram-negative cell wall is considerably lower than that of that of the cell’s Gram positive wall. There are only a few layers of peptidoglycan (2-8 millimeters) are visible in the cell … Read more
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Bacterial Cell Wall Characteristics of Peptidoglycan Peptidoglycan is a fundamental component of bacterial cell walls, forming a complex, mesh-like structure known as the sacculus. This structure is crucial for maintaining cell shape and integrity. Here are the key characteristics of peptidoglycan: Cell membrane of Gram-Positive Cell Wall The cell membrane of Gram-positive bacteria is a … Read more
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Archaeal Cell Wall Introduction One Membrane Archaea Double Membranes of Archaea What is S-Layer? The S-layer, or surface layer, is a fundamental component of the cell envelope in many archaea and some bacteria. It represents one of the most common cell wall variations, particularly among Crenarchaea. This layer consists primarily of proteins that self-assemble into … Read more