The classical pathway is a key immune system mechanism that plays an important role in defending the body from foreign invaders. It consists of a series of sequential interactions among complement components that result in the killing of target cells via a process known as cell lysis. The presence of an antibody attached to an antigen, … Read more
What is Alternative pathway of the complement system ? Activators of the alternative pathway Activators of the alternative pathway of complement activation include Steps of activation of alternative pathway Four serum proteins comprise the initial component of the alternative pathway: C3b, factor B, factor D, and properdin. 1. C3bB complex Formation 2. C3bB Cleavage 3. … Read more
An Overview of Complement System What is Lectin Pathway of Complement Activation? Components of Lectin Pathway 1. Mannose-binding lectin Structural subunits of mannan-binding lectin (MBL) and ficolins 2. MBL serum levels and MBL2 gene polymorphisms 3. Ficolins Ficolin-1 Ficolin-2 Ficolin-3 4. MBL-associated serine proteases Steps, Mechanism, Process of Lectin Pathway The lectin pathway, also known … Read more
1. The SXY–CIITA Regulatory System 2. TNF- And IFN-Induced Expression Of Mhc Class I 3. Expression Of Mhc Class Ib Genes 4. Other Regulatory Pathways Governing Mhc Class II Gene Expression
What is HLA Complex? What is H-2 Complex? Detailed Organization Of The H-2 Complex 1. Murine MHC Class I Genes 2. Murine 2-Microglobulin Gene 3. Murine MHC Class Ib Genes 4. Murine MHC Class II Genes 5. Murine MHC Class IIb Genes 6. Murine Non-MHC Genes in the MHC 7. Murine MHC Class III Genes … Read more
Antigen-Antibody (Ag-Ab) Interaction refers to the biochemical reaction that occurs between antibodies and specific antigens when they come into close proximity, typically within a distance of several nanometers. This interaction plays a critical role in the immune response against foreign substances and pathogens in the body. The binding of antibodies to specific antigens is facilitated … Read more
What is Antigen? Antigen Definition An antigen is a foreign molecule or substance that triggers an immune response in the body, leading to the production of antibodies. or An antigen is a substance that can stimulate an immune response in the body. It can be a molecule or a part of a molecule, such as … Read more
Antigen Presentation Definition Antigen-Presenting Cells Definition Types of Antigen-Presenting Cells Antigen-presenting cells fall into two categories: Antigen-presenting cells that contain MHC class II molecules, co-stimulatory molecules, and pattern recognition receptors are often referred to be “professional.” Non-professional APCs express molecules of MHC class I. 1. Professional Antigen-Presenting Cells a. Macrophages Activation of Macrophages For macrophages … Read more
In this article we will learn about Agglutination test definition, Types, Uses, Advantages, Disadvantages, Aim of Agglutination Test, Specimen collection, application of Agglutination test and finally Examples of Agglutination test. Agglutination Test Agglutination Test is a clinical assay used for the detection of Antibody or Antigen in body fluids such as saliva, urine, cerebrospinal fluid, … Read more
Immunodiffusion refers to the movement of antigen or antibody within the gel. Add the reactants to the wells. They diffuse to the area of lower/no concentration. A gradient of the reactants’ concentration forms as they diffuse into the gel. Immunoprecipitation takes place in a region with an equivalent concentration of both the antibody and antigen. This is represented by bands.
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