Complement System – Definition, Activation, Effects, Regulation

Complement System Definition, Activation, Effects, Regulation

Complement System Definition The complement system, also known as the complement cascade, is a component of the immune system that boosts the ability of antibodies and phagocytic cells to eliminate germs and damaged cells from an organism, stimulate inflammation, and assault the cell membrane of a pathogen. Properties of Complement  Complement demonstrates the following attributes: … Read more

Alternative Pathway of Complement System

Alternative Pathway of Complement System

What is Alternative pathway of the complement system ? Activators of the alternative pathway Activators of the alternative pathway of complement activation include  Steps of activation of alternative pathway Four serum proteins comprise the initial component of the alternative pathway: C3b, factor B, factor D, and properdin. 1. C3bB complex Formation 2. C3bB Cleavage 3. … Read more

Lectin Pathway of the Complement System

Lectin Pathway of the Complement System

An Overview of Complement System What is Lectin Pathway of Complement Activation? Components of Lectin Pathway 1. Mannose-binding lectin Structural subunits of mannan-binding lectin (MBL) and ficolins 2. MBL serum levels and MBL2 gene polymorphisms 3. Ficolins Ficolin-1 Ficolin-2 Ficolin-3 4. MBL-associated serine proteases Steps, Mechanism, Process of Lectin Pathway The lectin pathway, also known … Read more

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