Cryo Electron Microscopy – Principle, Procedure, Advantages, Limitations and Applications

Cryo Electron Microscopy - Principle, Strengths, Limitations and Applications

What is cryo-EM? Principle of cryo EM Types of cryo EM Cryo-electron microscopy (cryo-EM) is a collection of special methods. These are broadly categorized into two types, mainly cryo-transmission electron microscopy (cryo-TEM) and cryo-scanning electron microscopy (cryo-SEM). Each has its own advantage in the analysis of biological samples in their native state, frozen by cryo-preparation. … Read more

Migration in Fishes – Causes, Types, Methods, Significance

Migration in Fishes - Causes, Types, Methods, Significance

What is Fish migration? Fish migration is the active, regular movement of fish populations from one place to another, often over long distances and various environments. This behavior is critical to the survival of fish and is a function of varied ecological, environmental, and biological factors. Fish migration is specific to different fish species, ranging … Read more

Epi-Fluorescence Microscopy – Principle, Parts, Steps, Uses

The Fluorescence Light Path

Epi-Fluorescence Microscopy is defined as an optical imaging method, which is employed in laboratories for visualization of fluorescent-labeled samples. The technique is widely described as an essential approach, and it has been repeatedly applied in cell studies, tissue examinations, and even in material analysis. In this method, illumination is delivered from the same side / … Read more

Flame Photometer – Principle, Parts, Procedure, Applications

Flame Photometer - Principle, Parts, Procedure, Applications

What is Flame Photometer? Principle of Flame photometer The flame photometer is based on the principle that alkali and alkaline earth metal atoms are excited in the flame and that the light emitted when the excited atoms revert to the ground state can be measured. When you introduce a sample containing metal compounds into a … Read more

Difference between Telomere and Telomerase

Difference between Telomere and Telomerase

What is a Telomere? Telomeres are crucial components found at the ends of chromosomes. They are made up of repetitive nucleotide sequences that protect the genetic material from damage. Each time a cell divides, the telomeres shorten, playing a key role in cellular aging and health. Here’s a breakdown of what telomeres are, how they … Read more

Telomerase – Structure, Mechanism, Regulation, Functions

Telomeres and Telomerase

What is Telomerase? Telomerase (terminal transferase) is a ribonucleoprotein enzyme that extends telomeres, the repetitive nucleotide sequences at the ends of eukaryotic chromosomes. Telomeres function as protective caps, stopping chromosome ends from being erroneously perceived as DNA damage or from bonding with neighboring chromosomes. Most eukaryotes use telomerase to maintain their telomeres, but some organisms, … Read more

Telomeres – Structure, Aging, Shortening, Functions

Telomeres and Telomerase

What Are Telomeres (telomere)? At the ends of linear eukaryotic chromosomes are specialized structures called telomeres. DNA degradation is prevented by repetitive nucleotide sequences of the telomere, which caps and so stabilizes chromosomal DNA during cell division. The termini of chromosomes not only have no translation product but instead have a highly important role in … Read more

Gluconeogenesis – Definition, Steps, Reactions, Substrates, Importance

Gluconeogenesis - Definition, Steps, Reactions, Substrates, Importance

What is Gluconeogenesis? Gluconeogenesis Definition Gluconeogenesis is a metabolic process that synthesizes glucose from non-carbohydrate precursors, such as lactate, glycerol, and amino acids, primarily in the liver and kidneys, to maintain blood glucose levels during fasting or low carbohydrate intake. Location of Gluconeogenesis – Where does Gluconeogenesis Occur? Gluconeogenesis primarily occurs in the liver, which … Read more

Glycogenesis vs Glycogenolysis

Glycogenesis vs Glycogenolysis

What is Glycogenesis? What is Glycogenolysis? Differences between Glycogenesis and Glycogenolysis – Glycogenesis vs Glycogenolysis Glycogenesis and glycogenolysis are two key metabolic processes that govern the storage and release of glucose in the body. While they are related, they have opposing functions. Glycogenesis stores glucose in the form of glycogen, whereas glycogenolysis breaks down glycogen … Read more

Galactose Metabolism – Steps, Importance, Leloir Pathway

Galactose Metabolism - Steps, Importance, Leloir Pathway

What is Galactose? Galactose is a monosaccharide sugar that is an aldohexose. It is a C-4 epimer of glucose having the same structure as glucose, except that the atoms around carbon no. 4 are arranged differently. This sugar is around 65% of the sweetness of sucrose and is less sweet. It is paired with glucose … Read more