For each of the following set of cells, state the latest common progenitor cel that gives rise to both cell types — ( i) Monocytes and neutrophils (ii) Natural killer cells and B cells.
For each of the following set of cells, state the latest common progenitor cel that gives rise to both cell types — ( i) Monocytes and neutrophils (ii) Natural killer cells and B cells.
Answer
For each set of cells, the latest common progenitor cell that gives rise to both cell types is:
- Monocytes and Neutrophils:
- Common Myeloid Progenitor (CMP): Both monocytes and neutrophils arise from the common myeloid progenitor. The CMP differentiates into various myeloid lineage cells, including granulocytes (such as neutrophils) and monocytes, which can further differentiate into macrophages.
- Natural Killer (NK) Cells and B Cells:
- Common Lymphoid Progenitor (CLP): Both natural killer cells and B cells originate from the common lymphoid progenitor. The CLP gives rise to various lymphoid lineage cells, including NK cells, B cells, T cells, and other lymphoid cells.
In summary:
- Monocytes and Neutrophils: Common Myeloid Progenitor (CMP)
- Natural Killer Cells and B Cells: Common Lymphoid Progenitor (CLP)