Designed to enlarge things too tiny for the human eye to see, a microscope is a tool. It provides a portal to the hidden world of minute structures, allowing medical practitioners, teachers, and researchers to examine materials, cells, and creatures in until unheard-of clarity. Microscopes range significantly in kind, from simple to very sophisticated models. … Read more
What is Trinocular Microscope? Principle of Trinocular Microscope A trinocular microscope is similar to a binocular microscope but has an additional third eyepiece for a camera. It shines an LED light on the specimen and projects it onto a computer screen through a digital camera. The trinocular microscope is essentially a binocular microscope that focuses … Read more
An electron microscope is an instrument which produces an image of a sample by means of a beam of electrons. Optical microscopes use light to form an image, electron microscopes have greater resolution, and can be used to observe objects that are too small to be seen with an optical microscope. In a large variety … Read more
What is cryo-EM? Principle of cryo EM Types of cryo EM Cryo-electron microscopy (cryo-EM) is a collection of special methods. These are broadly categorized into two types, mainly cryo-transmission electron microscopy (cryo-TEM) and cryo-scanning electron microscopy (cryo-SEM). Each has its own advantage in the analysis of biological samples in their native state, frozen by cryo-preparation. … Read more
By Sourav Pan 2 revisions 13 min readby Sourav Pan
A game changer for the microscopic world is epi-fluorescence microscopy. Imagine being able to see cells as vibrant, dynamic creatures showing off their inner workings instead of just as static objects. This method, based on the principle of fluorescence, has opened up the hidden details of life at the cellular level and made the invisible … Read more
What is Working Distance? Working distance in an optical equipment such as a microscope is basically the space separating the lens and the thing you are viewing. You must pay close attention to the physical distance if you want to correctly see the specimen. This area is really important as it controls the proximity of … Read more
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