Which one or more of the following statements is/are correct in the processing of pre-mRNA in eukaryotes?

(A) 3′ → 5′ exonuclease activity is involved in the conversion of pre-mRNA to mRNA.
(B) 5′-capping and addition of 3′-poly A tail precede splicing.
(C) Splicing of pre-mRNA occurs via transesterification reaction.
(D) Alternative splicing can yield different mRNA products from the same pre-mRNA.

SouravAugust 18, 2024

Answer

Answer: (B) 5′-capping and addition of 3′-poly A tail precede splicing.
(C) Splicing of pre-mRNA occurs via transesterification reaction.
(D) Alternative splicing can yield different mRNA products from the same pre-mRNA.

Explanation:

Splicing occurs after 5′ capping and polyadenylation.

The splicing mechanism involves transesterification reactions.
Alternative splicing allows a single pre-mRNA to produce different mRNA variants.

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