How to use the Henderson-Hasselbalch equation with unknown volume?
How to use the Henderson-Hasselbalch equation with unknown volume?
Cite this post:
Sourav Pan. (2025, April 24). How to use the Henderson-Hasselbalch equation with unknown volume?. Biology Notes Online. Retrieved from https://biologynotesonline.com/qa/how-to-use-the-henderson-hasselbalch-equation-with-unknown-volume/
Sourav Pan. "How to use the Henderson-Hasselbalch equation with unknown volume?." Biology Notes Online, 24 April 2025, biologynotesonline.com/qa/how-to-use-the-henderson-hasselbalch-equation-with-unknown-volume/.
Sourav Pan. "How to use the Henderson-Hasselbalch equation with unknown volume?." Biology Notes Online (blog). April 24, 2025. https://biologynotesonline.com/qa/how-to-use-the-henderson-hasselbalch-equation-with-unknown-volume/.
Answered
If the volume is unknown but constant for both components, use the ratio of moles instead of concentrations: pH = pKa + log10(nA⁻/nHA), where nA⁻ and nHA are the moles of conjugate base and acid, respectively.
Cite this post:
Sourav Pan. (2025, April 24). How to use the Henderson-Hasselbalch equation with unknown volume?. Biology Notes Online. Retrieved from https://biologynotesonline.com/qa/how-to-use-the-henderson-hasselbalch-equation-with-unknown-volume/
Sourav Pan. "How to use the Henderson-Hasselbalch equation with unknown volume?." Biology Notes Online, 24 April 2025, biologynotesonline.com/qa/how-to-use-the-henderson-hasselbalch-equation-with-unknown-volume/.
Sourav Pan. "How to use the Henderson-Hasselbalch equation with unknown volume?." Biology Notes Online (blog). April 24, 2025. https://biologynotesonline.com/qa/how-to-use-the-henderson-hasselbalch-equation-with-unknown-volume/.