Biotechnology 2 Views 1 Answers
A mutant Gα protein with increased GTPase activity would (A) not bind to GTP (B) not bind to GDP (C) show increased signaling (D) show decreased signaling
A mutant Gα protein with increased GTPase activity would
(A) not bind to GTP
(B) not bind to GDP
(C) show increased signaling
(D) show decreased signaling
Answered
Answer: (D) show decreased signaling
Increased GTPase activity in a Gα protein means it will hydrolyze GTP to GDP more rapidly, leading to decreased signaling because the protein will be in its inactive GDP-bound state more often.
Did this page help you?