Microscope

Cryo Electron Microscopy – Principle, Procedure, Advantages, Limitations and Applications

Cryo Electron Microscopy - Principle, Strengths, Limitations and Applications

What is cryo-EM? Principle of cryo EM Types of cryo EM Cryo-electron microscopy (cryo-EM) encompasses several specialized techniques, primarily divided into two main types: cryo-transmission electron microscopy (cryo-TEM) and cryo-scanning electron microscopy (cryo-SEM). Each technique offers distinct advantages for studying biological specimens in their native, vitrified state. How does cryo EM work? – Protocol of … Read more

Electron Microscope – Principle, Types, Parts, Application, Diagram

Electron Microscope

An electron microscope is a type of microscope that uses a beam of electrons to create an image of a sample. Electron microscopes have a higher resolution than optical microscopes, which use light to form an image, and can be used to observe objects that are too small to be seen with an optical microscope. … Read more

Trinocular Microscope – Definition, Principle, Parts, Protocol, Uses

Trinocular Microscope - Definition, Principle, Parts, Protocol, Uses

What is Trinocular Microscope? Principle of Trinocular Microscope The principle of a trinocular microscope builds upon the fundamental concept of a binocular microscope, incorporating an additional third eyepiece that serves the purpose of connecting a microscope camera. The core principle involves the illumination of the specimen using light from an LED source, followed by the … Read more

Coarse Adjustment and Fine Adjustment Knob of Microscope

Coarse Adjustment and Fine Adjustment Knob of Microscope

What is Fine Adjustment Knob? Where is Fine Adjustment Knob located? What is Coarse Adjustment? Where is Coarse Adjustment located? In many microscopes, both the coarse and fine adjustment knobs are designed with a coaxial configuration, aligning them in a single line. This design allows for seamless switching between the two knobs without the need … Read more

Working Distance – Definition, Measurement, Types, Importance

Working Distance - Definition, Measurement, Types, Importance

What is Working Distance? What is working distance in Microscope? What Are the Different Types of Working Distances in a Microscope? The microscope has two main types of working distances: Both of these working distances help you observe things under the microscope and make sure they’re in focus. They define the space you have to … Read more

Pocket Microscope – Definition, Parts, Principle, Uses, Types

Pocket Microscope - Definition, Parts, Principle, Uses, Types

It is designed in a way that is compact and portable which is why it’s called a pocket’. They’re pocket-sized however some are bigger. Their size is not enough to be able to hold a mirror in order to put the image in the proper place. However, they contain a small stage where one can place an object to observe.  They’re portable so that they can be utilized by both professionals and amateurs according to the task they’re designed to fulfill.

Polarizing Microscopes – Principle, Definition, Parts, Applications

Polarizing Microscopes - Principle, Definition, Parts, Applications

What is Polarizing Microscope? A polarizing microscope is a type of microscope that uses polarized light to view specimens. It is commonly used to observe minerals, crystals, and other transparent or semi-transparent materials, as well as to analyze the structure and properties of these materials. Polarized light is light that vibrates in a specific plane, … Read more

How are samples prepared for a transmission electron microscope?

Transmission Electron  Microscope (TEM)

What is transmission electron microscope? A transmission electron microscope (TEM) is a powerful scientific instrument that is used to study the structure and properties of materials at the atomic and molecular level. It works by using a beam of electrons to create an image of a sample, which is then analyzed to study the sample’s … Read more

Light Microscope – Labeled Diagram, Definition, Principle, Types, Parts, Applications

Light Microscope - Labeled Diagram, Definition, Principle, Types, Parts, Applications

The study of microorganisms has come a long way since its inception, with advancements in technology and research driving the field of Microbiology forward. The ability to observe and understand microorganisms has given us an insight into the world of tiny organisms that are crucial to life on Earth. The first simple microscope was created … Read more

Inverted Fluorescent Microscope – Principle, Protocol, Parts, Uses

Inverted Fluorescent Microscope - Principle, Protocol, Parts, Uses

What is Inverted Fluorescent Microscope? Principle of Inverted Fluorescent Microscope The principle of an inverted fluorescent microscope lies in its ability to utilize fluorescence to visualize and study specimens, particularly living cells. This unique microscope operates based on several key principles. To begin, a halogen lamp serves as the primary light source for illuminating the … Read more

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