Which one or more of the following statements correctly describe(s) the changes upon the addition of puromycin during eukaryotic translation?

(A) Puromycin resembles the aminoacyl end of the charged tRNA.
(B) Puromycin occupies the A site of the translating ribosomes.
(C) Puromycin occupies the P site of the translating ribosomes.
(D) Puromycin occupies the E site of the translating ribosomes.

SouravAugust 18, 2024

Answer

Answer: (A) Puromycin resembles the aminoacyl end of the charged tRNA.
(B) Puromycin occupies the A site of the translating ribosomes.

Explanation:
Puromycin is an antibiotic that mimics the structure of an aminoacyl-tRNA and can bind to the A site of the ribosome, causing premature termination of the growing polypeptide chain.

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