Sourav PanAugust 18, 2024

Which of the following is/are consequence(s) of nitrous acid (HNO2_22) mediated deamination?

Which of the following is/are consequence(s) of nitrous acid (HNO $_2$ ) mediated deamination?

(A) Deamination of cytosine, adenine, and guanine
(B) GC-to-AT transitions
(C) AT-to-GC transitions
(D) Addition of an alkyl group to the bases

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Sourav PanAugust 18, 2024

Answered

Answer: (A) Deamination of cytosine, adenine, and guanine
(B) GC-to-AT transitions
(C) AT-to-GC transitions

Explanation:
Nitrous acid causes the deamination of cytosine, adenine, and guanine, leading to transitions from GC to AT and AT to GC in DNA.

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