When is DNA replicated?

DNA is replicated during the S phase of interphase, which is one of the stages in the cell cycle. The S phase comes after the G1 phase and before the G2 phase. This timing ensures that the cell has an accurate copy of its DNA to distribute to the daughter cells during mitosis. Replication of the DNA occurs in a highly regulated and coordinated process involving several enzymes and proteins to ensure fidelity and prevent errors.