Do pipette tips dissolve in DMF?
Do pipette tips dissolve in DMF?
Answered
Pipette tips are generally made from materials such as polypropylene or polystyrene, which are known for their resistance to a range of solvents, including many acids and bases. However, when exposed to Dimethylformamide (DMF), a polar aprotic solvent, the material composition of the pipette tip must be considered. Polypropylene and polystyrene are not highly resistant to DMF, and prolonged exposure can lead to degradation of the tip. DMF can cause some plastics to soften or swell, and in extreme cases, the material may begin to break down, affecting the integrity of the pipette tip. Therefore, while standard pipette tips may not immediately dissolve in DMF, they can degrade over time. In situations where DMF is being used frequently, it is advisable to use pipette tips made from materials that are more resistant to this solvent, such as those made from fluoropolymers like PTFE or PFA, which are highly resistant to a broad range of solvents, including DMF.
BNO Team