Genetics is the branch of biology that studies genes, heredity, and variation in living organisms. It explores how traits are passed from parents to offspring through genes, which are segments of DNA that carry instructions for building and maintaining an organism.
Key areas in genetics include:
Molecular Genetics: Studies how DNA, RNA, and proteins function in cells.
Mendelian Genetics: Focuses on inheritance patterns based on Gregor Mendel’s laws.
Population Genetics: Examines how genetic variations occur within populations over time.
Genomic Studies: Involves sequencing and analyzing whole genomes to understand genetic influence on traits.
What is RNA splicing? In order for mRNA to be translated into a protein, RNA splicing removes the intervening, non-coding sections of genes (introns) from pre-mRNA and links the protein-coding sequences (exons) together. Facts of RNA splicing What is Intron? What is Exon? What is Spliceosome? Types of Spliceosome There are two types of spliceosomes: … Read more
What is RNA? Definition of RNA RNA, or Ribonucleic acid, is a nucleic acid molecule that plays a crucial role in gene expression and protein synthesis. It is a single-stranded molecule composed of nucleotides, including adenine (A), cytosine (C), guanine (G), and uracil (U). RNA carries genetic information from DNA and acts as a template … Read more
What is Nucleoside? A nucleoside is a molecule composed of a pentose sugar linked to a nitrogenous base or glycosylamine. It can be considered as a nucleotide without a phosphate group. Nucleosides are essential components of DNA and RNA, playing a vital role in the storage and transmission of genetic information. In DNA, the nucleosides … Read more
What is gab operon? Structure of gab operon There are three structural genes that make up the gab operon: Regulation of gab operon Differential Regulation of Promoters The expression of the genes in the operon is controlled by three promoters that work in different ways. Two of these promoters are controlled by the sigma factor … Read more
What is a Monohybrid Cross? A monohybrid cross is a genetic cross between individuals who differ in only one trait or allele set. It is the study of inheritance patterns for a single trait, typically with a focus on a single gene with two opposing alleles. In a monohybrid cross, two heterozygous (having two distinct … Read more
Gene mapping, also known as genome mapping or genome mapping, is an important technique used by scientists to establish the location of genes on a chromosome. It entails determining the location of a gene, quantifying the distance between genes, and establishing landmarks within the genome. Just like landmarks help us make our way around a … Read more
DNA has long been regarded as a critical component in gene therapy. A recent discovery, however, has thrown light on a strange type of DNA that persists in its surrounding environment without any protein or lipid bonds. Because of its possible applications in gene therapy trials, this phenomenon, known as “naked DNA,” has piqued the … Read more
Gene silencing, a mechanism of reducing or suppressing gene expression, is critical in managing gene expression in cells. Genes, which are responsible for protein production, have distinct expression spectra that determine the amount of protein produced by a gene in a specific cell type. When the expression profile of genes is altered, however, it can … Read more
Gene therapy is a groundbreaking field of medicine that focuses on the modification of cells to treat or prevent genetic disorders by repairing or replacing defective genetic material. It holds the potential to cure a wide range of genetic diseases by directly addressing the underlying genetic abnormalities. In this series of articles, we aim to … Read more
What is lac Operon? Jacques Monod (1910–1976) began studying bacterial growth and regulation in the late 1930s. He selected E. coli as a model bacteria and eventually concentrated on genes involved in E. coli’s growth on lactose. Francois Jacob joined him in his studies roughly 15 years later (1920–2013). As a result of their research, … Read more
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