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The cGMP pathway, short for cyclic guanosine monophosphate pathway, is a crucial signaling mechanism in cells. It involves the synthesis of cGMP from GTP (guanosine triphosphate) through the action of the enzyme guanylate cyclase. cGMP acts as a secondary messenger, similar to cyclic AMP (cAMP), and plays a vital role in various physiological processes. One … Read more
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What is Photosystem I (PS1)? Definition of Photosystem I (PS1) Photosystem I (PSI) is a crucial protein complex in oxygenic photosynthesis, primarily found in algae, plants, and cyanobacteria. It functions by capturing light energy to drive the transfer of electrons across the thylakoid membrane, from plastocyanin to ferredoxin. This process contributes to the synthesis of … Read more
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What are G Protein Coupled Receptors? Structure of G Protein Coupled Receptors Classification of G Protein Coupled Receptors The G protein-coupled receptor (GPCR) superfamily encompasses a vast array of receptors, with at least 831 human genes, approximately 4% of the protein-coding genome, predicted to code for GPCRs. Despite the lack of detectable shared sequence homology … Read more
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What is Lineweaver–Burk plot? The Lineweaver–Burk plot, commonly referred to as the double reciprocal plot, stands as a foundational concept within the domain of biochemistry. Stemming from the renowned Michaelis–Menten equation, which pertains to enzyme kinetics, this plot was innovatively introduced by Hans Lineweaver and Dean Burk in the year 1934. Delving into its essence, … Read more
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What is Induced Fit Model? Evidences Supporting Induced Fit Model The Induced Fit Model has garnered significant attention in the realm of biochemistry, and various pieces of evidence support its validity. This model posits that proteins, including enzymes, are not static or rigid structures. Instead, they exhibit dynamic properties, allowing them to adapt and change … Read more
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What is Lock and Key Model? The Lock and Key Model Concept The “Lock and Key Model” is a fundamental concept in enzymology, introduced by Emil Fischer in 1899. This model provides an analogy to explain the specificity exhibited by enzymes during their interactions with substrates. In this analogy, the enzyme is likened to a … Read more
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What are Vitamins? Definition of Vitamins Vitamins are organic molecules essential in small amounts for an organism’s proper metabolic function, which are typically obtained through the diet as they cannot be synthesized by the organism in sufficient quantities. History and nomenclature of Vitamins The history and nomenclature of vitamins have their roots in the early … Read more
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The retinoids, a group of molecules related to the dietary retinol (vitamin A) , are essential for vision and reproduction, growth and the maintenance of epithelial tissue. They also play an essential part in the immune system. Retinoic acid, which is derived by oxidation of retinol plays a major role in the action of the … Read more
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What is Vitamin D? Definition of Vitamin D Vitamin D is a fat-soluble secosteroid that plays a crucial role in calcium absorption in the gut, promoting bone health and regulating various other biological functions. It can be naturally obtained from sunlight exposure, certain foods, and supplements. Once ingested or synthesized in the skin, it undergoes … Read more
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What is Vitamin E? Definition of Vitamin E Vitamin E is a fat-soluble antioxidant essential for human health that protects cell membranes from damage by reactive oxygen species and plays a role in immune function, skin health, and vision. It encompasses a group of eight compounds, including four tocopherols and four tocotrienols. Chemical structures of … Read more