The early detection of diseases is crucial for effective treatment, and molecular diagnostics serves as a pivotal tool in this regard. This term encompasses a range of diagnostic techniques that assess an individual’s health at a molecular level. Specifically, molecular diagnostics focuses on the identification and quantification of genetic sequences—often referred to as biomarkers—found in … Read more
Animal cells are ideal for recombinant protein production because they possess the ability to carry out post-translational modifications, a process that is often lacking in bacterial cells. This capability makes animal cells essential for the commercial synthesis of various biological products, including antibodies, hormones, growth factors, cytokines, and viral coat proteins, which are used in … Read more
What is Transgenic Animal? Definition of Transgenic Animal A transgenic animal is an organism that has had a foreign gene (transgene) deliberately inserted into its genome, allowing the gene to be expressed and passed on to future generations. Steps for Production of Transgenic Animals The production of transgenic animals involves a detailed and systematic approach … Read more
What are Biosensors? Definition of Biosensors A biosensor is a device that detects biological changes and converts them into an electrical signal, typically by combining a biological sensing element with a transducer for applications like medical diagnostics or environmental monitoring. Components of Biosensors Biosensors consist of several key components that work together to detect biological … Read more
By Sourav Pan 16 revisions 20 min readby Sourav Pan
What is High Throughput Sequencing (HTS)? Working Principle of High Throughput Sequencing (HTS) High-throughput sequencing (HTS) technologies High-throughput sequencing (HTS) technologies have revolutionized genomic research by enabling rapid and detailed analysis of genetic material. The principal HTS technologies can be categorized into next-generation sequencing (NGS) and third-generation sequencing. Each of these technologies has distinct methodologies, … Read more
Proteins are fundamental to virtually all biological processes, serving as the building blocks of cells, enzymes catalyzing biochemical reactions, and key regulators of cellular functions. Understanding protein structures, functions, and interactions is essential for advancing biological research, drug development, and medical diagnostics. The sheer complexity and diversity of proteins, however, pose significant challenges for researchers … Read more
The DNA Data Bank of Japan (DDBJ) is a pivotal resource in the realm of genomics and bioinformatics, playing a crucial role in advancing scientific research and collaboration. Established in 1987, DDBJ was created to support the growing need for accessible, comprehensive genomic data. Its mission is to collect, maintain, and disseminate DNA sequence data, … Read more
By Sourav Pan 2 revisions 20 min readby Sourav Pan
The EMBL Nucleotide Sequence Database, commonly referred to as EMBL-Bank, is a pivotal resource in the realm of molecular biology. As an extensive repository of nucleotide sequences, EMBL-Bank plays a crucial role in biological research by providing a comprehensive and up-to-date collection of DNA sequences from a diverse range of organisms. This database is invaluable … Read more
Curious about how to get gene sequences from NCBI? Whether you’re a student, researcher, or just a genetics enthusiast, NCBI is an amazing resource for all things genetic. It can be a bit overwhelming at first, but don’t worry—I’m here to guide you through the whole process. In this easy-to-follow, step-by-step guide, we’ll walk you … Read more
The National Center for Biotechnology Information (NCBI) is a part of the U.S. National Library of Medicine, which is itself a branch of the National Institutes of Health (NIH). It provides access to a wealth of information in the fields of biotechnology and biomedicine. Some key resources offered by NCBI include: NCBI’s resources are widely … Read more
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