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Pipette tips themselves do not have a fixed expiration date, but their quality and performance can degrade over time. Most manufacturers recommend storing pipette tips in their original packaging in a cool, dry place, away from UV light, chemicals, and extreme temperatures, to maintain their integrity. Over time, exposure to certain environmental conditions (e.g., heat, humidity) can cause plastic tips to become brittle or warped, which may affect their ability to fit snugly on pipettes or cause inaccuracies in liquid handling. For disposable tips, it is also essential to ensure they are not contaminated or damaged before use. If stored correctly and used within a reasonable period, pipette tips should function well for an extended time, though it is generally advisable to check for any signs of deterioration before using them.