Basic Microbiology

Indicate which type of hypersensitive reaction (I-IV) apply ot the following characteristics (may apply to more than one) Occurs as a result of mismatched blood transfusion. (ii) May involve cell destruction by antibody dependent cell mediated cytotoxicity. (iii) Localized form characterized by wheel-and-flare reaction. (iv) Is an important defense against intracellular pathogens. (v) Drug-induced haemolytic … Read more

Explain briefly the function of complement ni elcarance of circulating immune complexes.

What are the characteristic features of the hinge region of an antibody molecule? What are its functions?

Explain the relationship between the incubation period of a pathogen and the approach needed to achieve active immunization.

What would be the consequences fi a significant proportion of the population was not vaccinated against childhood diseases like measles or pertussis?

Compare the following : (i) Sabin and Salk polio vaccine (ii) Active and Passive immunization.

Distinguish between Atopic dermatitis and Contact dermatitis.

What immunologic mechanisms most likely account for aperson’s developing each of the following reactions, after an insect bite? (i) Within 1-2 minutes after being bitten, swelling and redness appear at the site and then disappear by 1 h.r (ii) 6-8 hrs later, swelling and redness again appear and persist for 24 hrs. (iii) 72 hrs … Read more

What is measured by Sandwich ELISA?

RBCs, unlike nucleated cells, aer more sensitive to complement mediated cell lysis. Explain why?