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The dissociation constant Kd for ligand binding to the receptor is 10⁻⁷ M. The concentration of ligand required for occupying 10% of receptors is (A) 10⁻⁶ M (B) 10⁻⁷ M (C) 10⁻⁸ M (D) 10⁻⁹ M
The dissociation constant Kd for ligand binding to the receptor is 10⁻⁷ M. The concentration of ligand required for occupying 10% of receptors is
(A) 10⁻⁶ M
(B) 10⁻⁷ M
(C) 10⁻⁸ M
(D) 10⁻⁹ M
Answer
Answer: (B) 10⁻⁷ M
The dissociation constant Kd represents the concentration of ligand at which 50% of receptors are occupied. For 10% occupancy, the concentration is close to Kd, which is 10⁻⁷ M.
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