Identify the enzyme that catalyzes the following reaction: α-Ketoglutarate + NADH + NH4+ + H+ → Glutamate + NAD+ + H2O (A) Glutamate synthetase (B) Glutamate oxoglutarate aminotransferase (C) Glutamate dehydrogenase (D) α-ketoglutarate deaminase
Identify the enzyme that catalyzes the following reaction:
α-Ketoglutarate + NADH + NH4+ + H+ → Glutamate + NAD+ + H2O
(A) Glutamate synthetase
(B) Glutamate oxoglutarate aminotransferase
(C) Glutamate dehydrogenase
(D) α-ketoglutarate deaminase
Answer
Answer: (C) Glutamate dehydrogenase
This reaction is catalyzed by glutamate dehydrogenase, which facilitates the conversion of α-ketoglutarate to glutamate with the reduction of NADH to NAD+. The other enzymes listed do not catalyze this specific reaction.