Pathways

What is Gluconeogenesis? Gluconeogenesis Definition Gluconeogenesis is a metabolic process that synthesizes glucose from non-carbohydrate precursors, such as lactate, glycerol, and amino acids, primarily in the liver and kidneys, to maintain blood glucose levels during fasting or low carbohydrate intake. Location of Gluconeogenesis – Where does Gluconeogenesis Occur? Gluconeogenesis primarily occurs in the liver, which … Read more

What do you mean by Fate of Pyruvate? Pyruvate, the end product of glycolysis, represents a central intermediate in cellular metabolism. Glycolysis is a sequence of enzyme-catalyzed reactions in which glucose is broken down into two molecules of pyruvate, generating ATP and NADH in the process. This pathway, also known as the Embden-Meyerhof-Parnas (EMP) pathway, … Read more

What is glycolysis? Definition of glycolysis Glycolysis is a metabolic process in which glucose, a six-carbon sugar, is broken down into two three-carbon pyruvate molecules, producing a net gain of two ATP and two NADH molecules. This anaerobic pathway occurs in the cytosol and is a key step in cellular energy production. Major Features of … Read more

The cGMP pathway, short for cyclic guanosine monophosphate pathway, is a crucial signaling mechanism in cells. It involves the synthesis of cGMP from GTP (guanosine triphosphate) through the action of the enzyme guanylate cyclase. cGMP acts as a secondary messenger, similar to cyclic AMP (cAMP), and plays a vital role in various physiological processes. One … Read more

What is Glycolysis? Glycolysis 10 Steps Glycolysis is a central metabolic pathway that facilitates the breakdown of glucose into pyruvate through a series of enzymatic reactions. This process is methodically organized into ten distinct steps, divided into two primary phases: the Preparatory phase and the Payoff phase. Preparatory Phase: Payoff Phase: In summary, glycolysis is … Read more

What is Urea Cycle? Definition of Urea Cycle The urea cycle is a series of biochemical reactions in the liver that convert ammonia, a toxic byproduct of protein metabolism, into urea, a less harmful compound that is excreted in the urine. Urea Cycle Reactions/Urea Cycle Steps The urea cycle is a critical metabolic pathway that operates primarily … Read more

What is the Cori Cycle? Cori Cycle Definition The Cori Cycle is a metabolic pathway in which lactate produced by anaerobic glycolysis in muscles is transported to the liver, converted back into glucose, and then returned to the muscles for energy production. This cycle plays a crucial role in maintaining energy balance during periods of … Read more

What is Feedback Inhibition? Definition of Feedback Inhibition Feedback inhibition is a cellular regulatory mechanism in which the end product of a biochemical pathway inhibits the activity of the first enzyme in that pathway, preventing overproduction of the end product. Enzymes, Substrates, and Products Process of Feedback Inhibition Feedback inhibition, a cardinal regulatory mechanism within … Read more

What is Uronic Acid Pathway or Glucuronic pathway? Overview The uronic acid pathway stands as a distinctive cytoplasmic thoroughfare within cellular metabolism, orchestrating intricate transformations that hold pivotal significance for various physiological processes. As we embark on an exploration of this biochemical route, we uncover its multifaceted roles and far-reaching implications for cellular health and … Read more

What is Pentose Phosphate Pathway? Pentose Phosphate Pathway Definition The Pentose Phosphate Pathway (PPP) is a metabolic pathway parallel to glycolysis that produces NADPH, pentoses (5-carbon sugars), and ribose 5-phosphate, a precursor for nucleotide synthesis. It plays a crucial role in both cellular biosynthesis and the defense against oxidative stress. Location of Pentose Phosphate Pathway … Read more