5′ Capping and Polyadenylation – Definition, Mechanism

5' Capping and Polyadenylation - Definition, Mechanism

What is 5′ capping? The unique cap structure of eukaryotic mRNA is composed of 7-methylguanosine residues connected by a 5′-5′ triphosphate bridge. Structure of 5′ cap 5’ Capping process The starting point for capping with 7-methylguanylate is the unmodified, triphosphate-terminated 5′ end of an RNA molecule. Following the last nucleotide are three phosphate groups connected … Read more

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