Sourav PanDecember 20, 2024

You made a mutation in your cells in which you inhibited the formation of Ligase enzyme. What will happen to the DNA replication in the cells? – A. Nothing, DNA will replicate normally – B. Semiconservative replication will not happen – C. DNA primers will not form – D. Replication bubble will not form

You made a mutation in your cells in which you inhibited the formation of Ligase enzyme. What will happen to the DNA replication in the cells?
– A. Nothing, DNA will replicate normally
– B. Semiconservative replication will not happen
– C. DNA primers will not form
– D. Replication bubble will not form

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Sourav PanDecember 20, 2024

Answered

B. Semiconservative replication will not happen. DNA ligase is essential for sealing nicks in the sugar-phosphate backbone, which is necessary for the completion of lagging strand synthesis. Without ligase, replication is incomplete.

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