Basic Microbiology 8 Views 1 Answers
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Sourav PanSeptember 4, 2024

Why is Oral Poliovirus Vaccine (OPV) preferred over Inactivated Poliovirus Vaccine (IPV)?

Why is Oral Poliovirus Vaccine (OPV) preferred over Inactivated Poliovirus Vaccine (IPV)?

Sourav Pan
Sourav PanSeptember 4, 2024

Answered

OPV is preferred over IPV in many settings because it is easier to administer (oral) and provides both systemic and local immunity (in the gut), which helps in preventing the spread of poliovirus in the community. Additionally, OPV is less expensive and can contribute to herd immunity. However, IPV is used in settings where the risk of vaccine-associated paralytic poliomyelitis (VAPP) with OPV is a concern.

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