where does the kreb cycle take place

The Krebs cycle takes place in the mitochondrial matrix of eukaryotic cells. This matrix is a gel-like substance enclosed by the inner mitochondrial membrane, containing the necessary enzymes and cofactors for the cycle’s reactions. In prokaryotic cells, which lack mitochondria, the cycle occurs in the cytoplasm. The mitochondrial matrix’s proximity to the inner membrane enables efficient transfer of the high-energy electrons produced by the cycle to the electron transport chain for ATP production.