What’s the enzyme that untwists and unzips DNA during replication?

The enzyme that untwists and unzips the DNA during replication is helicase. Helicase unwinds the DNA double helix by breaking the hydrogen bonds between complementary base pairs, creating two single-stranded DNA templates. This process occurs at the replication fork, where the two strands are separated and ready for replication. By unwinding the DNA, helicase enables other enzymes, such as DNA polymerase, to access the individual strands and begin synthesizing new complementary DNA strands.