What is the steps of DNA replication?

Sourav PanDecember 6, 2024

Answered

The steps of DNA replication include:
1. Initiation: Helicase unwinds the DNA at the origin of replication, creating a replication bubble.
2. Priming: Primase synthesizes an RNA primer on both strands to provide a starting point for DNA synthesis.
3. Elongation: DNA polymerase adds nucleotides to the 3′ end of the primer, extending the new strand in the 5′ to 3′ direction. On the leading strand, synthesis is continuous, while on the lagging strand, Okazaki fragments are formed.
4. Termination: The RNA primers are removed, gaps are filled by DNA polymerase I, and the final strands are sealed by DNA ligase to form two identical DNA molecules.