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Sourav PanApril 24, 2025

What does the Henderson-Hasselbalch equation explain?

What does the Henderson-Hasselbalch equation explain?

Sourav Pan
Sourav PanApril 24, 2025

Answered

The equation explains the quantitative relationship between the pH of a solution and the ratio of the concentrations of a weak acid and its conjugate base. It illustrates how the pH of a buffer solution depends on the acid-base equilibrium and how changes in the ratio of [A⁻]/[HA] affect the pH. This understanding is fundamental in acid-base chemistry and the design of buffer systems.

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