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The Krebs cycle plays a central role in cellular respiration by oxidizing acetyl-CoA into carbon dioxide while capturing high-energy electrons in the form of NADH and FADH₂. These electrons drive ATP synthesis via oxidative phosphorylation. The cycle also produces a molecule of GTP (or ATP) and provides biosynthetic precursors for amino acid, nucleotide, and lipid synthesis. It functions as a metabolic hub, integrating catabolic and anabolic pathways essential for maintaining cellular energy and biochemical balance.
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