Bacteriology 1 Views 1 Answers
What are some mechanisms that bacteria use to resist the effect of antimicrobials?
What are some mechanisms that bacteria use to resist the effect of antimicrobials?
Answered
Bacteria resist antimicrobials through several mechanisms: 1. Enzyme production: Some bacteria produce enzymes, like β-lactamases, that break down the antimicrobial agent. 2. Efflux pumps: Bacteria can pump out the antimicrobial before it can act. 3. Alteration of target sites: Bacteria may mutate their target sites to prevent the antimicrobial from binding effectively. 4. Biofilm formation: Bacteria in biofilms are protected from antibiotics due to limited penetration and increased resistance. 5. Reduced permeability: Bacteria can modify their cell wall or membrane to prevent the antimicrobial from entering the cell.
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