Q.33 Which of the following statement(s) about eukaryotic DNA topoisomerase is/are correct?
Which of the following statement(s) about eukaryotic DNA topoisomerase is/are correct?
(A) Topoisomerase I creates transient single-strand breaks
(B) Topoisomerase I creates transient double-strand breaks
(C) Topoisomerase II creates transient single-strand breaks
(D) Topoisomerase II creates transient double-strand breaks
Answer
Answer: (A) Topoisomerase I creates transient single-strand breaks, (D) Topoisomerase II creates transient double-strand breaks
Explanation: Topoisomerase I and II manage DNA supercoiling by creating transient breaks.