Is the Krebs cycle anaerobic?

Sourav PanApril 18, 2025

Answered

No, the Krebs cycle is an aerobic pathway, meaning it requires the presence of oxygen. While the cycle itself does not consume oxygen directly, it relies on the electron transport chain, which requires oxygen as the final electron acceptor to produce ATP. Without oxygen, the electron transport chain cannot function, which prevents the Krebs cycle from continuing due to the accumulation of NADH and FADH₂.

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