How to calculate pKa using the Henderson-Hasselbalch equation?
How to calculate pKa using the Henderson-Hasselbalch equation?
Cite this post:
Sourav Pan. (2025, April 24). How to calculate pKa using the Henderson-Hasselbalch equation?. Biology Notes Online. Retrieved from https://biologynotesonline.com/qa/how-to-calculate-pka-using-the-henderson-hasselbalch-equation/
Sourav Pan. "How to calculate pKa using the Henderson-Hasselbalch equation?." Biology Notes Online, 24 April 2025, biologynotesonline.com/qa/how-to-calculate-pka-using-the-henderson-hasselbalch-equation/.
Sourav Pan. "How to calculate pKa using the Henderson-Hasselbalch equation?." Biology Notes Online (blog). April 24, 2025. https://biologynotesonline.com/qa/how-to-calculate-pka-using-the-henderson-hasselbalch-equation/.
– Rearrange the equation to solve for pKa: pKa = pH – log₁₀([A⁻]/[HA]) – Determine the pH of the solution and the concentrations of [A⁻] and [HA]. – Calculate the ratio [A⁻]/[HA] and its logarithm. – Subtract this value from the pH to find the pKa.
Cite this post:
Sourav Pan. (2025, April 24). How to calculate pKa using the Henderson-Hasselbalch equation?. Biology Notes Online. Retrieved from https://biologynotesonline.com/qa/how-to-calculate-pka-using-the-henderson-hasselbalch-equation/
Sourav Pan. "How to calculate pKa using the Henderson-Hasselbalch equation?." Biology Notes Online, 24 April 2025, biologynotesonline.com/qa/how-to-calculate-pka-using-the-henderson-hasselbalch-equation/.
Sourav Pan. "How to calculate pKa using the Henderson-Hasselbalch equation?." Biology Notes Online (blog). April 24, 2025. https://biologynotesonline.com/qa/how-to-calculate-pka-using-the-henderson-hasselbalch-equation/.
