How much ATP is produced in Krebs cycle?

Sourav PanApril 18, 2025

Answered

The Krebs cycle produces 1 direct ATP (or GTP) per cycle turn through substrate-level phosphorylation. Through oxidative phosphorylation, 3 NADH contribute approximately 7.5 ATP and 1 FADH₂ contributes about 1.5 ATP, bringing the total to approximately 10 ATP equivalents per cycle. As each glucose molecule yields two turns of the Krebs cycle (via two acetyl-CoA molecules), the total ATP yield per glucose molecule is about 20 ATP equivalents.

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