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Sourav PanDecember 18, 2024

How is the aging process linked to telomeres?

How is the aging process linked to telomeres?

Sourav Pan
Sourav PanDecember 18, 2024

Answered

The aging process is closely linked to the shortening of telomeres. As cells divide over time, their telomeres shorten, which eventually leads to the cessation of cell division. This shortening serves as a mechanism that limits the lifespan of cells, contributing to the aging process. When telomeres become critically short, cells enter a state of senescence (permanent growth arrest) or undergo apoptosis (programmed cell death), both of which contribute to tissue degeneration and the physical signs of aging. Shortened telomeres have also been linked to age-related diseases such as cardiovascular disease, dementia, and certain forms of cancer.

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