Does the Henderson-Hasselbalch equation apply to buffering solutions?

Sourav PanApril 24, 2025

Answered

Absolutely. The equation is fundamental in understanding and calculating the pH of buffer solutions. It relates the pH to the pKa (or pKb) and the ratio of the concentrations of the conjugate base to the weak acid (or conjugate acid to the weak base), providing insight into the buffer’s capacity to resist pH changes.

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