Can you use Kw in the Henderson-Hasselbalch equation?

Sourav PanApril 24, 2025

Answered

While the Henderson-Hasselbalch equation itself does not directly involve Kw (the ionization constant of water), Kw is related to the equation through the relationship between pKa and pKb: pKa + pKb = 14. This relationship allows for the conversion between acid and base dissociation constants, which can be useful when applying the equation to basic buffers.

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