Which one of the following pairs of amino acids is NOT incorporated in a polypeptide chain?
Which one of the following pairs of amino acids is NOT incorporated in a polypeptide chain?
(A) 4-Hydroxyproline and γ-carboxyglutamate
(B) γ-Carboxyglutamate and desmosine
(C) Ornithine and citrulline
(D) 4-Hydroxyproline and 5-hydroxylysine
Answer
Answer: (C) Ornithine and citrulline
Explanation:
Ornithine and citrulline are not standard amino acids incorporated into proteins during translation. They are intermediates in the urea cycle, whereas the other options include modified amino acids (like 4-Hydroxyproline and γ-carboxyglutamate) that can be incorporated into polypeptide chains in specific contexts.