Which enzyme is used both in gluconeogenesis and glycogenolysis?

Sourav PanDecember 15, 2024

Answered

The enzyme phosphogluco-mutase is involved in both gluconeogenesis and glycogenolysis. In glycogenolysis, phosphoglucomutase catalyzes the conversion of glucose-1-phosphate (produced from glycogen breakdown) to glucose-6-phosphate. In gluconeogenesis, phosphoglucomutase plays a role in converting glucose-6-phosphate into intermediates that are used to synthesize glucose from non-carbohydrate precursors. Thus, phosphoglucomutase is an essential enzyme in both processes, aiding in the interconversion of glucose derivatives.

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