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Glycogenolysis occurs when the body needs glucose to meet immediate energy demands, such as during fasting, physical exercise, or between meals when blood glucose levels are low. It is triggered by the release of hormones like glucagon (from the pancreas) and epinephrine (from the adrenal glands), which activate the enzymes involved in glycogen breakdown. Glycogenolysis also occurs during intense physical activity when muscle cells require a rapid supply of glucose for energy.
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