What is the difference between a knockout animal and a transgenic animal?

SouravSeptember 20, 2024

Answer

The main differences between a knockout animal and a transgenic animal are:

Definition:
- Transgenic Animal: An animal that has been genetically modified to carry a gene from another species. This gene can provide new traits or characteristics.
- Knockout Animal: An animal in which a specific gene has been deliberately inactivated or “knocked out” to study the effects of losing that gene.
Purpose:
- Transgenic: Typically used to introduce new traits, study gene function, or produce proteins for medical purposes.
- Knockout: Used to understand the role of a specific gene in development, disease, or other biological processes.
Genetic Modification:
- Transgenic: Involves the addition of foreign genetic material.
- Knockout: Involves the removal or disruption of an existing gene.

In summary, transgenic animals incorporate foreign genes, while knockout animals have specific genes disabled.

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