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In the Krebs cycle, acetyl-CoA (a 2-carbon molecule) combines with oxaloacetate (a 4-carbon molecule) to form citrate (a 6-carbon compound). The cycle then undergoes a series of enzyme-driven steps, involving decarboxylation and oxidation, which generate 3 NADH, 1 FADH₂, 1 ATP (or GTP), and release 2 CO₂ molecules. The cycle regenerates oxaloacetate, allowing it to accept another molecule of acetyl-CoA and repeat.
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