Genetics 5 Views 1 Answers

Sourav Pan🥇 GoldDecember 6, 2024
What does ligase do in DNA replication?
What does ligase do in DNA replication?
Please login to save the post
Please login to submit an answer.

Sourav Pan🥇 GoldMay 15, 2025
In DNA replication, the enzyme DNA ligase plays a crucial role in joining the ends of DNA fragments. Specifically, it is involved in the lagging strand synthesis, where replication occurs in short fragments known as Okazaki fragments. After DNA polymerase synthesizes these fragments, DNA ligase seals the gaps between them by forming phosphodiester bonds, thus creating a continuous strand. DNA ligase is also involved in repairing breaks in the DNA backbone during replication and after DNA damage.
0
0 likes
- Share on Facebook
- Share on Twitter
- Share on LinkedIn